The U.S.-Israeli war with Iran is rattling businesses worldwide, driving up energy prices, squeezing supplies of critical raw materials and raising questions about the reliability of trade routes critical to the flow of goods from food to car parts. Below are the main disruptions so far: TRAVEL CHAOS The war has closed much of the region's airspace and crippled Dubai and Doha airports, two of the world's busiest transit hubs, stranded tens of thousands of passengers and forced airlines to cancel about 40,000 flights--the travel industry's biggest disruption since the COVID-19 pandemic.